RASD1 antibody

Catalog No. ABIN6568710

This anti-RASD1 antibody is a Rabbit Polyclonal antibody detecting RASD1 in WB. Suitable for Mouse and Human.

Quick Overview for RASD1 antibody (ABIN6568710)

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RASD1 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human RASD1

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RASD1

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Alternative Name: RASD1

Background:

Synonyms: Activator of G protein signaling 1,Activator of G protein signaling,Activator of G-protein signaling 1,AGS 1,AGS1,Dexamethasone induced ras related protein 1,Dexamethasone-induced ras protein 1,Dexamethasone-induced Ras-related protein 1,Dexras 1,MGC:26290,RAS dexamethasone induced 1,Ras protein, Dexamethasone-induced, 1,Ras related protein,RASD 1,Rasd1,RASD1

Background: This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 31kDa

Calculated_MW: 13kDa/31kDa

Gene ID: 51655

UniProt: Q9Y272